The International Institute
of Molecular Mechanisms and Machines
Polish Academy of Sciences
POSTDOCTORAL RESEARCHER
„Structure-function analysis of the spliceosome”
Laboratory of RNA Biology
Head: Prof. Magda Konarska
POSITION IN PROJECT
Postdoctoral Researcher
LOCATION
Warsaw, Poland
SCIENTIFIC DISCIPLINE
Molecular biology, biochemistry, genetics
NUMBER OF POSITIONS
1
PROJECT TITLE
“Regenerative Mechanisms for Health" ReMedy
SUBPROJECT TITLE:
„Structure-function analysis of the spliceosome”
PROJECT LEADER
Magda Konarska, Laboratory of RNA Biology
SUBPROJECT DESCRIPTION
We are interested in the function of the spliceosome, its dynamic changes during splicing, and possible in response to stress conditions. The spliceosomal catalytic center undergoes dynamic changes during the catalytic phase of splicing; these changes affect splicing catalysis, altering splicing fidelity and thus affecting alternative splicing patterns. Using recent cryo-EM information of yeast S. cerevisiae spliceosome as a model, we focus on substrate-spliceosome interactions at the catalytic center. These studies will lead to new approaches for modulating alternative splicing patterns.
JOB TYPE
Full-time position, stipend/contract
REMUNERATION/STIPEND AMOUNT/MONTH:
8 900,00 – 11 650,00 PLN gross, depending on experience.
POSITION STARTS ON
1st June 2021 or later upon mutual agreement
APPLICATION DEADLINE
19th May 2021
YOUR FUTURE KEY RESPONSIBILITIES:
-
Perform experiments using biochemical, molecular biology or genetic techniques (independently and in collaboration with other team members),
-
Participate in experimental design and data analysis,
-
Participate in the data preparation and writing of manuscripts,
-
Actively participate in lab meetings, scientific seminars and conferences.
IF YOU ARE:
-
PhD degree in molecular biology, biophysics, biochemistry or related fields of life sciences,
-
Maximum 5 years sice PhD,
-
Solid knowledge and familiarity with laboratory techniques in at least one of the following disciplines: molecular biology, biochemistry, cell biology, genetics, transcriptomics,
-
Very good command of English,
-
Motivation and passion for experimental work.
... PLEASE APPLY.
And let us present the details to you.
REQUIRED DOCUMENTS (ENGLISH ONLY)
-
Motivation letter,
-
CV with the list of publications,
-
Contact details of three scientific supervisors or another referee/s
(including the direct PhD supervisor). -
Please apply using the form below.
-
Please send all the documents as a single .pdf file.
-
We will contact selected candidates only.
FNP PROGRAMME
-
Project is carried out within the International Research Agendas Programme of the Foundation for Polish Science
SEND APPLICATION
Postdoctoral Researcher
„Structure-function analysis of the spliceosome”
Process concluded
